In 1963, Swedish researchers discovered the often deadly lung disease called, Alpha-1 Antitrypsin Deficiency, or, Alpha-1. Prior to that, the symptoms of Alpha-1 misled doctors to misdiagnose it as some other respiratory problem such as emphysema, or asthma. But Alpha-1 is a genetic defect in which the body does not make enough of a particular protein that protects the lungs and liver from damage. As a result, life-threatening consequences can occur. Researchers estimate that about 90 percent of people with this disease are unaware they even have it. In this program, we'll take a close look at Alpha-1, explore its history, and hear from experts and patients about the inroads that have been made in better managing this disease.