The intricate history of a beautiful antique violin is traced from its creation in Cremona, Italy, in 1681, where a legendary violin maker (Carlo Cecchi) paints it with his dead wife's blood to keep her memory alive, to an auction house in modern-day Montreal, where it draws the eye of an expert appraiser (Samuel L. Jackson). Over the years between, the violin travels through four different countries, where it has a profound impact on all those who own it.