When Mary Cane-Honeysett, a talented elderly artist living alone in London, suffers a stroke, she develops tremors in her hands that prevent her from holding a paintbrush steady. Depressed that she can no longer paint with the same tight, detailed style for which she has become known, she gives up art entirely. Struggling with the after-effects of her stroke, Mary also faces the problem of maneuvering around her house, which has become unmanageable in her physical condition. She must now deal with the difficult reality of selling the home she has lived in since she was a child. BRUSHSTROKE follows Mary's journey as she confronts new challenges, restarts her life, and tries to put paint back on the canvas.