Host David Yetman sets out to explore the Chihuahuan Desert and the re gion near the Rio Grande River in Big Bend National Park. The river de fines the border between the U.S. and Mexico. After an informal border crossing in a rickety boat dubbed "La Enchilada," viewers take a burr o trek to Boquillas, one of the most remote villages in Mexico. During the trip, they meet some local characters, including a veteran paleon tologist who digs up deep-sea marine mammals in the middle of the dese rt.